Clinicopathological Significance of STAT3 and p-STAT3 among 91 Patients with Adenocarcinoma of the Esophagogastric Junction

Table 2

Western blot detection for the correlation between STAT3/p-STAT3 expression and clinical features of AEG.

Clinical features	Patients ()	STAT3			p-STAT3
		STAT3 expression			p-STAT3 expression
Gender			0.032	0.198		0.256	0.884
Male	24
Female	6
Age			0.996	0.114		0.611	0.156
≥60	23
<60	7
Differentiation			2.508	0.091		-1.25	0.184
High+medium	10
Low	20
pT			-1.624	0.226		-2.458	0.011
pT1+ pT2	14
pT3+ pT4	16
pN			-8.278	0.225		-3.146	0.04
−	10
+	20
pTNM			-10.023	0.044		-3.974	0.01
pI + pII	11
pIII	19

: or test; AEG: adenocarcinoma of the esophagogastric junction; STAT3: signal transduction and activators of transcription factor 3; pT: tumor invasion; pN: lymph node metastasis; pTNM: tumor stage.