Clinicopathological Significance of STAT3 and p-STAT3 among 91 Patients with Adenocarcinoma of the Esophagogastric Junction

Table 4

Results of cox regression multivariate 5-year survival analysis of the patients with AEG.

Clinical features		SE	Wald		HR	95.0% CI for HR
Gender	-0.675	0.437	2.387	0.122	0.509	0.216~1.199
Age	0.280	0.372	0.567	0.451	1.323	0.638~2.743
Differentiation	1.035	0.411	6.338	0.012	2.814	1.258~6.296
pT	0.544	0.450	1.459	0.227	1.722	0.713~4.161
pN	1.851	0.598	9.566	0.002	6.366	1.970~20.572
pTNM	-0.979	0.535	3.351	0.067	0.376	0.132~1.072
Chemotherapy	-0.121	0.427	0.080	0.777	0.886	0.384~2.046
Radiotherapy	-0.160	0.427	0.141	0.707	0.852	0.369~1.967
STAT3	0.188	0.620	0.092	0.762	1.207	0.358~4.071
p-STAT3	1.314	0.563	5.448	0.020	3.722	1.234~11.223

: regression coefficient; SE: standard error; Wald: Wald value; HR: hazard ratio; CI: confidence interval; AEG: adenocarcinoma of the esophagogastric junction; pT: tumor invasion; pN: lymph node metastasis, pTNM: tumor stage; STAT3: signal transduction and activators of transcription factor 3; p-STAT3: phosphorylated signal transduction and activators of transcription factor 3.