Research Article
TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population
Table 4
Relationship between genotype and allele distributions and components of MS.
| | Normal TG () (%) | Elevated TG () (%) | | Normal BP () (%) | Elevated BP () (%) | | Normal FPG () (%) | Elevated FPG () (%) | | Normal weight () (%) | Abdominal obesity () (%) | | Normal HDL-C () (%) | Abnormal HDL-C () (%) | |
| Genotype | | | | | | | | | | | | | | | | CC | 387 (56.0) | 688 (52.9) | | 66 (53.2) | 1009 (54.0) | | 567 (53.9) | 508 (54.2) | | 104 (53.3) | 971 (54.2) | | 687 (52.2) | 388 (57.6) | | CT | 259 (37.5) | 512 (39.4) | 0.351 | 49 (39.5) | 722 (38.7) | 0.989 | 408 (38.7) | 363 (38.7) | 0.972 | 76 (39.0) | 695 (38.7) | 0.965 | 527 (40.0) | 244 (36.2) | 0.060 | TT | 45 (6.5) | 100 (7.7) | | 9 (7.3) | 136 (7.3) | | 78 (7.4) | 67 (7.1) | | 15 (7.7) | 130 (7.1) | | 103 j(7.8) | 42 (6.2) | | Dominant effect | | | | | | | | | | | | | | | | CC | 387 (56.0) | 688 (52.9) | 0.202 | 66 (53.2) | 1009 (54.0) | 0.926 | 567 (53.9) | 508 (54.2) | 0.893 | 104 (53.3) | 971 (54.2) | 0.880 | 687 (52.2) | 388 (57.6) | 0.023 | CT+TT | 304 (44.0) | 612 (47.1) | | 58 (46.8) | 858 (46.0) | | 486 (46.1) | 430 (45.8) | | 91 (46.7) | 825 (45.8) | | 630 (47.8) | 286 (42.4) | | Recessive effect | | | | | | | | | | | | | | | | CC+CT | 646 (93.5) | 1200 (92.3) | 0.366 | 115 (92.7) | 1731 (92.7) | 1.000 | 975 (92.6) | 871 (92.9) | 0.863 | 180 (92.3) | 1666 (92.9) | 0.772 | 1214 (92.2) | 632 (93.8) | 0.203 | TT | 45 (6.5) | 100 (7.7) | | 9 (7.3) | 136 (7.3) | | 78 (7.4) | 67 (7.1) | | 15 (7.7) | 130 (7.1) | | 103 (7.8) | 42 (6.2) | | Allele | | | | | | | | | | | | | | | | C | 1033 (74.7) | 1888 (72.6) | 0.153 | 181 (73.0) | 2740 (73.4) | 0.941 | 1542 (73.2) | 1379 (73.5) | 0.858 | 284 (72.8) | 2637 (73.4) | 0.801 | 1901 (72.2) | 1020 (75.7) | 0.018 | T | 349 (25.3) | 712 (27.4) | | 67 (27.0) | 994 (26.6) | | 564 (26.8) | 497 (26.5) | | 106 (27.2) | 955 (26.6) | | 733 (27.8) | 328 (24.3) | |
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BP: blood pressure; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; FPG: fasting plasma glucose; ā ā is the number of subjects. |