Research Article
TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population
Table 5
Relationship between genotype and allele distribution and ischemic stroke in the population.
| | Whole people | MS group | Control group | | N () (%) | Y () (%) | | N () (%) | Y () (%) | | N () (%) | Y () (%) | |
| | Genotype | | | | | | | | | | | CC | 1650 (54.5) | 14 (37.8) | | 1065 (54.3) | 10 (33.4) | | 585 (54.7) | 4 (57.1) | | | CT | 1174 (38.7) | 16 (43.2) | 0.012 | 758 (38.7) | 13 (43.3) | 0.004 | 416 (38.9) | 3 (42.9) | 1.000 | | TT | 206 (6.8) | 7 (19.0) | | 138 (7.0) | 7 (23.3) | | 68 (8.4) | 0 (0) | | | Dominant effect | | | | | | | | | | | CC | 1650 (54.5) | 14 (37.8) | 0.047 | 1065 (54.3) | 10 (33.4) | 0.026 | 585 (54.7) | 4 (57.1) | 1.000 | | CT+TT | 1380 (45.5) | 23 (62.2) | | 896 (45.7) | 20 (66.6) | | 464 (45.3) | 3 (42.9) | | | Recessive effect | | | | | | | | | | | CC+CT | 2824 (93.2) | 30 (81) | 0.012 | 1823 (93.0) | 23 (76.7) | 0.005 | 1001 (91.6) | 7 (100) | 1.000 | | TT | 206 (6.8) | 7 (19.0) | | 138 (7.0) | 7 (23.3) | | 68 (8.4) | 0 (0) | | | Allele | | | | | | | | | | | C | 4474 (73.8) | 44 (59.5) | 0.008 | 2888 (73.6) | 33 (55.0) | 0.003 | 1586 (74.2) | 11 (78.6) | 1.000 | | T | 1586 (26.2) | 30 (40.5) | | 1034 (26.4) | 27 (45.0) | | 552 (25.8) | 3 (21.4) | |
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Y: with ischemic stroke; N: without ischemic stroke; “ ” is the number of subjects. |
