Research Article

[Retracted] Activated Hepatic Stellate Cells Promote the M1 to M2 Macrophage Transformation and Liver Fibrosis by Elevating the Histone Acetylation Level

Figure 1

Lactate levels are elevated in mice with liver fibrosis. (a) The 8-week-old mice were treated with CCl4 for 6 weeks, and the fibrosis was assessed by H&E, Masson, and Sirius red staining. Scale bars are 100 μm. (b) Kit to detect lactate level in the liver tissue. At least 3 liver sections were analyzed per mouse (number of mice: ). (c, d) Western blot showing expression of acetylation and α-SMA in the livers of mice treated with CCl4. (e) Detection of the expression levels of M2 macrophage surface markers CD163, Arg1, and IL-10 in the liver by ELISA. , .
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