Identification of Significant Genes and Pathways for the Chronic and Subacute Cutaneous Lupus Erythematosus via Bioinformatics Analysis

Table 4

The top hub genes of CCLE.

Gene symbol	Description	Degree of connectivity
CXCL10	C-X-C motif chemokine ligand 10	60
IRF7	Interferon regulatory factor 7	56
IFIT3	Interferon-induced protein with tetratricopeptide repeats 3	54
CTLA4	Cytotoxic T lymphocyte-associated protein 4	50
ISG15	ISG15 ubiquitin-like modifier	50
OAS2	2-5-Oligoadenylate synthetase 2	50
RASD2	Radical S-adenosyl methionine domain-containing 2	48
CCL5	C-C motif chemokine ligand 5	48
GBP1	Guanylate-binding protein 1	46
OAS1	2-5-Oligoadenylate synthetase 1	46