hsa_circ_0139402 Promotes Bladder Cancer Progression by Regulating hsa-miR-326/PAX8 Signaling

<div>hsa_circ_0139402 is overexpressed in BC patients and cell lines. (a) High-throughput sequencing analysis of the expression of circRNA in 3 pairs of BC tissues; (b) QRT-PCR analysis of the expression levels of hsa_circ_0139402 in BC tissues compared with normal tissues; (c) the expression levels of hsa_circ_0139402 in BC tissues with lymph node metastasis compared with those without metastasis; (d) QRT-PCR analysis of the expression levels of hsa_circ_0139402 in BC cells (UMUC3, EJ, 5637, and J82) and human immortalized uroepithelium cells (SV-HUC-1); (e) QRT-PCR analysis of the expression of hsa_circ_0139402 and mRNA PTCH1 after RNase R treatment in 5637 cells; (f) hsa_circ_0139402 was predominately located in the cytoplasm by FISH. 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Disease Markers

fig1

Figure 1

Figure 1: hsa_circ_0139402 Promotes Bladder Cancer Progression by Regulating hsa-miR-326/PAX8 Signaling 