Label-Free Proteomics of Oral Mucosa Tissue to Identify Potential Biomarkers That Can Flag Predilection of Precancerous Lesions to Oral Cell Carcinoma: A Preliminary Study

Figure 3

Expression level change of differentially expressed proteins. (1) Increased ratio of cancer/leukoplakia: (a) L-lactate dehydrogenase A chain, (b) WD repeat-containing protein 1, and (c) plectin; (2) decreased ratio of cancer/leukoplakia: (d) thioredoxin 1 and (e) spectrin alpha chain, nonerythrocytic 1; (3) increased ratio of cancer/erythroplakia: (f) L-lactate dehydrogenase A chain; and (4) decreased ratio of of cancer/erythroplakia: (g) heat shock 70 kDa protein 1B, (h) aldehyde dehydrogenase 2, (i) peroxiredoxin 1, and (j) spectrin alpha chain, nonerythrocytic 1. denotes value < 0.05 and denotes value < 0.01.

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