Label-Free Proteomics of Oral Mucosa Tissue to Identify Potential Biomarkers That Can Flag Predilection of Precancerous Lesions to Oral Cell Carcinoma: A Preliminary Study

Figure 4

Functional annotation of differentially expressed proteins with biological functions and pathways. TXN, PRDX1, HSPA1B, and LDHA are involved as a response to oxidative stress. SPTAN1 and WDR1 regulate actin filament depolymerization. LDHA and ALDH2 are involved in carbon metabolism pathways such as glycolysis and pyruvate metabolism.