Research Article

Identifying Hub Genes and miRNA-mRNA Regulatory Networks in Mice Infected with H1N1 Influenza Virus

Table 4

Main information of real hub genes.

RankGene symbolFull nameFunction

1Ifit3Interferon-induced protein with tetratricopeptide repeats 3Predicted to enable RNA-binding activity and to be involved in interferon-beta pathway.
2Stat2Signal transducer and activator of transcription 2Involved in negative regulation of type I interferon-mediated signaling pathway and type I interferon signaling pathway.
3Irf7Interferon regulatory factor 7Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA-binding activity.