Research Article

Arterial Hypertension and Its Consequences Are the Main Predictors of Embolic Stroke of Undetermined Source

Table 3

The main results of the univariate statistical analysis based on the instrumental examination data.

Asymptomatic volunteers (control group)Patients with ESUS (study group)Significance (р)

Сonduction disturbance (bundle branch blocks, ECG) (n (%))3 (6.5%), N = 4625 (23.8%), N = 1050.012
Heart rate (bpm) (ECG) (mean ± SD)63.65 ± 10.5, N = 4668.73 ± 12, N = 1050.014
Left atrium enlargement (echocardiography) (n (%))9 (22.0%), N = 4145 (47.9%), N = 940.005
Right atrium enlargement (echocardiography) (n (%))4 (10.0%), N = 4032 (34.4%), N = 930.003
Left ventricular hypertrophy, all subtypes (echocardiography) (n (%))8 (21.1%), N = 3838 (60.3%), N = 63<0.0005
Eccentric left ventricular hypertrophy (echocardiography) (n (%))1 (12.5%), N = 82 (5.3%), N = 380.444
Pulmonary arterial systolic pressure (mm Hg) (echocardiography) (mean ± SD)25.83 ± 5.21, N = 4128.88 ± 6.59, N = 940.002
Left ventricle end-diastolic volume (ml) (echocardiography) (mean ± SD)101 ± 17, N = 41103 ± 23, N = 940.606
Left ventricle ejection fraction (%) (echocardiography) (mean ± SD)63 ± 5, N = 4164 ± 6, N = 940.363
Left ventricle end-systolic length (mm) (echocardiography) (mean ± SD)28.98 ± 3.43, N = 4130.73 ± 3.30, N = 940.018
Subcortical microbleeds absence (MRI)45 (95,7%), N = 4781 (72.3%), N = 1120.006
Deep microbleeds absence (MRI)42 (89.4%), N = 4781 (72.3%), N = 1120.101
Periventricular white matter lesions absence (MRI, Fazekas score 0)30 (63.8%), N = 4748 (42.9%), N = 1120.088
Width of the third ventricle (MRI, mm)5.02 ± 2.07, N = 477.57 ± 2.54, N = 112<0.0005
Central atrophy signs absence (MRI)39 (83.0%), N = 4764 (57.1%), N = 1120.041
Right medial temporal lobe atrophy (MRI, MTA score 0)29 (61.7%), N = 4740 (35.7%), N = 1120.028
Left medial temporal lobe atrophy (MRI, MTA score 0)29 (61.7%), N = 4748 (42.9%), N = 1120.049

N, overall patients number. Significant p values are highlighted in bold.