Endothelial Progenitor Cells Affect the Growth and Apoptosis of Renal Cells by Secreting Microvesicles Carrying Dysregulated miR-205 and miR-206

Figure 1

Screening of potential therapeutic miRNAs. (a) Determination of UAE in rats. (b) The sample GSE110231 was analyzed by GEO to screen miRNAs. Heat map shows differentially expressed miRNAs in diabetic rats compared with healthy rats. The blue band represents low expression, and the red band represents high expression. The blue part is low expression, and the red part is high expression. (c–o) RT-qPCR analysis of miR-1-3p (c), miR-9a-5p (d), miR-206 (e), miR-205 (f), miR-98-5p (g), miR-216a-3p (h), miR-451-5p (i), miR-466b-5p (j), miR-490-3p (k), miR-743b-3p (l), miR-881-3p (m), miR-1949 (n), and miR-219a-2-3p (o) expression in vivo. . GEO: Gene Expression Omnibus; RT-qPCR: real-time quantitative polymerase chain reaction; UAE: urinary albumin excretion; miR: microRNA.

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