Research Article

Differential Plasma Proteins Identified via iTRAQ-Based Analysis Serve as Diagnostic Markers of Pancreatic Ductal Adenocarcinoma

Table 2

List of the 30 differentially expressed proteins in PDAC.

No.AccessionDescriptionCoverage (%)Unique peptides valueFold change (cancer/control)

1P02679Fibrinogen gamma chain (FGG)56300.037750.802208
2P06727Apolipoprotein A-IV (APOA4)76330.0064250.759622
3P68871Hemoglobin subunit beta (HBB)9580.0116490.605902
4P01859Immunoglobulin heavy constant gamma-2 (IGHG2)5370.0078080.79011
5P69905Hemoglobin subunit alpha (HBA1)92110.0198230.634655
6P0DOX5Immunoglobulin gamma-1 heavy chain (fragment)4170.0002230.772435
7P02042Hemoglobin subunit delta (HBD)7650.0055680.640484
8Q16610Extracellular matrix protein 1 (ECM1)22110.0016410.81717
9P32119Peroxiredoxin-2 (PRDX2)2340.0156710.746562
10P69891Hemoglobin subunit gamma-1 (HBG1)4450.031020.689903
11Q13885Tubulin beta-2A chain (TUBB2A)1210.0119060.778568
12P00918Carbonic anhydrase 2 (CA2)2050.000190.759015
13P18428Lipopolysaccharide-binding protein (LBP)730.0381520.700106
14Q02985Complement factor H-related protein 3 (CFHR3)610.0453690.806503
15Q15365Poly(rC)-binding protein 1 OS=Homo sapiens (PCBP1)1320.0462260.677007
16P07195L-Lactate dehydrogenase B chain (LDHB)720.0309360.79955
17P24821Tenascin (TNC)230.0467690.832112
18P78371T-Complex protein 1 subunit beta (CCT2)410.0451810.716738
19P21796Voltage-dependent anion-selective channel protein 1 (VDAC1)710.0042230.812415
20P52272Heterogeneous nuclear ribonucleoprotein M (HNRNPM)210.0420550.778395
21Q5T619Zinc finger protein 648 (ZNF648)210.0024920.612377
22P01009Alpha-1-antitrypsin (SERPINA1)68350.0350571.212389
23P02748Complement component C9 (C9)32170.0217671.20568
24P02545Prelamin-A/C (LMNA)830.0036941.544529
25P18065Insulin-like growth factor-binding protein 2 (IGFBP2)1440.0398771.247822
26Q8WUD1Ras-related protein Rab-2B OS=Homo sapiens (RAB2B)710.0138811.488336
27P30086Phosphatidylethanolamine-binding protein 1 (PEBP1)610.0095461.239642
28P08134Rho-related GTP-binding protein RhoC (RHOC)510.0274161.295181
29P84243Histone H3.3 (H3-3A)510.0005542.23796
30Q5T011KICSTOR complex protein SZT2 (SZT2)010.0422251.297243