Research Article
Coagulation Dysfunction in Patients with Liver Cirrhosis and Splenomegaly and Its Countermeasures: A Retrospective Study of 1522 Patients
Table 2
Types of coagulation disorders and treatment outcomes in patients with cirrhosis and splenomegaly.
| | Group | Number of coagulation disorders | Types of coagulation disorders | Number of patients, (%) | Treatment results | | Effective, (%) | Dead, (%) |
| | 1 | One | PT (>15 s) | 124 | 122 | 2 (1.6) | | APTT (>40 s) | 41 | 41 | 0 (0.0) | | FIB (<2 g/L) | 305 | 289 | 16 (5.2) | | TT (>21 s) | 36 | 34 | 2 (5.6) | | Subtotal | 506 (41.3) | 486 (96.0) | 20 (4.0) |
| | 2 | Two | PT+APTT | 93 | 89 | 4 (4.3) | | PT+PTA | 68 | 65 | 3 (4.4) | | PT+FIB | 91 | 85 | 6 (6.6) | | PT+TT | 16 | 15 | 1 (6.3) | | FIB+APTT | 8 | 8 | 0 | | FIB+TT | 8 | 8 | 0 | | APTT+TT | 3 | 3 | 0 | | Subtotal | 287 (23.4) | 273 (95.1) | 14 (4.9) |
| | 3 | Three or more | PT+APTT+FIB | 30 | 27 | 3 (10.0) | | PT+FIB+TT | 7 | 7 | 0 | | PT+APTT+TT+PTA | 6 | 5 | 1 (16.6) | | FIB+APTT+TT | 5 | 5 | 0 | | PT+APTT+FIB+PTA | 235 | 230 | 5 (2.1) | | PT+FIB+APTT+TT | 9 | 8 | 1 (11.1) | | PT+FIB+APTT+TT | 140 | 130 | 10 (7.1) | | Subtotal | 432 (35.3) | 412 (95.8) | 20 (4.6) |
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Abbreviations: APTT: activated partial thromboplastin time; Fib: fibrinogen; PT: prothrombin time; PTA: prothrombin activity; TT: thrombin time.
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