Association between Serum Cys C and PTB Cavitation
Table 1
Characteristics of the three groups.
Noncavitary PTB ()
Cavitary PTB ()
HC ()
value
Gender (M/F)
22/20
46/15ab
23/19
0.026
Age (years)
31 (22.75–38.5)
36 (28–55.5)
35.5 (29–44.25)
0.085
BMI (kg/m2)
18.80 (17.70–21.25)
18.47 (17.19–19.98)
NA
0.457
Current/ex/never smoking
11/2/29
29/3/29
NA
0.084
Current/ex/never drinking
21/1/20
34/2/25
NA
0.789
Onset of symptoms
Cough, number (%)
80.95%
88.52%
NA
0.284
Hemoptysis, number (%)
9.52%
37.70%b
NA
0.001
Sweat, number (%)
28.57%
24.59%
NA
0.652
Fever, number (%)
33.33%
22.95%
NA
0.244
CT findings
Both lung lesions, number (%)
66.67%
72.13%
NA
0.552
Pleural thickening, number (%)
54.76%
49.18%
NA
0.578
Clinical laboratory tests
Sputum positive, number (%)
7.14%
29.51%b
NA
0.006
CRP (ng/L)
21.74 (8.54–71.11)
14.93 (2.48–57.07)
NA
0.167
Cys C (mg/L)
0.79 (0.67–0.88)
0.87 (0.72–0.96)ab
0.79 (0.74–0.83)
0.022
BUN (mmol/L)
3.55 (2.80–4.46)
3.87 (3.09–4.61)
4.28 (3.50–4.81)
0.091
UA (umol/L)
305.50 (242.75–356.75)
301.00 (247.00–365.00)
307.00 (255.25–347.50)
0.984
CR (umol/L)
61.00 (54.50–70.00)
68.00 (57.50–76.00)
67.00 (55.00–76.00)
0.078
GFR (ml/min)
128.00 (118.00–144.00)
126.23 (109.00–140.00)
116.00 (106.00–137.00)
0.076
BMI: body mass index; CRP: C-reactive protein; Cys C: cystatin C; BUN: blood urea nitrogen; UA: uric acid; CR: creatine; GFR: glomerular filtration rate; NA: not available. ; statistic significant (Kruskal-Wallis test with Dunn multiple test comparison or Chi-square test); a, compared with healthy control; b, compared with noncavitary PTB.
