[Retracted] The Nine RNA Methylation Regulatory Gene Signature Is Associated with the Pathogenesis of Atrial Fibrillation by Modulating the Immune Microenvironment in the Atrial Tissues

Figure 2

Characterization of the nine AF risk-related RNA methylation regulatory gene signature. (a) Univariate logistic regression analysis shows the expression levels of RNA methylation regulatory genes in the AF samples of the merge cohort. The data is represented as odds ratio (OR) with 95% confidence interval (95% CI). The regulatory genes with values below 0.05 represent those with significant differences in expression levels between AF and SR samples. (b) LASSO coefficient profiles of 20 RNA methylation regulatory genes. (c) Selection of the tuning parameter (lambda, ) using 10-fold cross-validation wherein the binomial deviances from the LASSO regression cross-validation model were plotted against log (). (d–h) ROC curve analyses show the diagnostic power of the 9-AF-related gene risk score in the (d) merge cohort, (e) GSE41177, (f) GSE14975, (g) GSE115574, and (h) GSE79768 datasets.

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