Research Article
Low Plasma Levels of Hyaluronic Acid Might Rule Out Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation
| | Patient’s characteristics | SOS () | Non-SOS () | value (Mann–Whitney/Fisher’s exact) |
| | Age (years, median (range)) | 59 (25-70) | 51 (20-68) | 0.198 | | Female sex, (%) | 3 (43%) | 19 (48%) | 0.999 | | Type of HSCT, (%) | | | 0.395 | | Autologous | 1 (14%) | 16 (40%) | | | Allogeneic | 6 (86%) | 24 (60%) | | | Type of donor, (%) | | MUD | 0 | 8 (20%) | 0.155 | | MRD | 2 (29%) | 8 (20%) | 0.999 | | Haploidentical | 4 (57%) | 8 (20%) | 0.184 | | Conditioning regimen, (%) | | Intensity | | | 0.173 | | Myeloablative | 3 (43%) | 30 (75%) | | | Nonmyeloablative | 4 (57%) | 10 (25%) | | | Containing busulfan | 5 (71%) | 22 (55%) | 0.682 | | Containing cyclophosphamide | 4 (57%) | 17 (43%) | 0.684 | | Containing TBI | 0 | 2 (5%) | 0.999 | | Previous chemotherapy lines, median (range) | 3 (2-9) | 2 (1-5) | 0.019 | | Previous autologous HSCT, (%) | 2 (29%) | 3 (8%) | 0.154 | | Hematologic disease, (%) | | | 0.986 | | Acute myeloid leukemia | 2 (29%) | 11 (27%) | | | Acute lymphoid leukemia | 0 | 5 (13%) | | | Myelodysplastic syndrome | 1 (14%) | 3 (8%) | | | Multiple myeloma | 1 (14%) | 4 (10%) | | | Non-Hodgkin lymphoma | 2 (29%) | 9 (23%) | | | Hodgkin lymphoma | 1 (14%) | 7 (18%) | | | Aplastic anemia | 0 | 1 (3%) | |
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MRD: matched related donor; MUD: matched unrelated donor.
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