Integrative Bioinformatics Analysis Identifies DDX60 as a Potential Biomarker for Systemic Lupus Erythematosus

Figure 6

Volcano plot and the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analyses of DDX60-related DEGs. (a) Volcano plot showed the 199 upregulated (red) and 23 downregulated (green) genes. (b) Bubble diagram illustrates the top significantly enriched pathways of KEGG analysis with an adj value < 0.05. The size of the nodes indicates the number of enriched genes, and the colors represent the significant levels of enrichment. (c) Bar plot illustrates the top 30 significantly enriched GO terms. The length of the bar indicates the number of enriched genes in this GO term, and the colors represent the significance levels of enrichment.

(a)

(b)

(c)