Research Article

Inhibition of Mast Cell Degranulation in Atopic Dermatitis by Celastrol through Suppressing MRGPRX2

Figure 1

Inhibition of DNFB-induced atopic dermatitis by Celastrol was reversed by overexpression of MRGPRX2. (a) HE staining was performed to unfold the tissue damage. (b) The skin thickness was analyzed. (c) Toluidine blue staining was used to observe mast cells. (d) The number of mast cells was counted. Yellow arrows represent hair follicles, and red arrows represent mast cells. suggests .
(a)
(b)
(c)
(d)