Research Article

NNMT Is an Immune-Related Prognostic Biomarker That Modulates the Tumor Microenvironment in Pan-Cancer

Table 1

Analysis of the correlation between NNMT and gene markers of TAMs, M1 macrophages, and M2 macrophages in TIMER.

Cell typeGene markersCOADHNSCOVSTAD
NonePurityNonePurityNonePurityNonePurity
CorCorCorCorCorCorCorCor

TAMCCL20.730.680.370.330.480.260.590.57
CD680.470.400.250.190.420.140.230.19
CD800.510.430.370.330.360.160.270.22
IL100.520.460.350.300.470.270.450.42

M1 macrophageINOS (NOS2)-0.14-0.21-0.17-0.130.020.73-0.060.37-0.050.27-0.080.13
IRF50.260.26-0.030.54-0.040.4410.110.06-0.030.630.230.24
ARG20.020.65-0.020.75-0.24-0.170.18-0.140.13-0.11

M2 macrophageCD1630.670.60.470.420.430.190.420.38
VSIG40.680.610.500.450.520.2920.490.47
MRC10.550.470.450.380.360.110.080.380.35
MS4A4A0.640.570.500.450.490.2520.460.42

None: correlation coefficient without adjustment; Purity: correlation adjusted by tumor purity; Cor: value of Spearman’s correlation. . . . .