Meta-Analysis of Assessment of Total Oxidative Stress and Total Antioxidant Capacity in Patients with Periodontitis

Table 4

The pre and posttreatment mean values of TAC in various biological fluid samples in patients with periodontitis in the included studies of quantitative synthesis.

Study name	Unit	Sample type	Periodontitis (pretreatment)		Periodontitis (posttreatment)		p-Value
			Mean ± SD or median (upper–lower value)	Sample size	Mean ± SD or median (upper–lower value)	Sample size
Chapple et al. [8]	μMTeq	Plasma	483 ± 111	35	489 ± 119	32	0.56
		GCF	632 ± 343		1,015 ± 549		0.001
Guentsch et al. [11]	μmol/ml	Saliva	0.37 ± 0.24	15	0.44 ± 0.22	15	<0.05
Kim et al. [14]	μM	Saliva	335.7 ± 36.6	7	326.8 ± 53.2	7	>0.05
Akpinar et al. [22]	mmol Trolox equiv./L	GCF	0.1 (0–0.1)	15	0.1 (0–0.1)	15	<0.05
Novaković et al. [23]	µmol/l	Saliva	0.4 ± 0.24	21	0.66 ± 0.35	21	<0.01
Bostanci et al. [27]	μmol Trolox equivalent/l	Serum	0.09 (0.07–0.11)	15	1.65 (1.55–2.62)	15	<0.05
		GCF	1.45 (1.23–2.10)		0.05 (0.04–0.09)
Shirzaiy et al. [30]	µmol/l	Saliva	0.655 ± 0.281	31	0.962 ± 0.287	31	<0.001
Thomas et al. [31]	mmol/l	Serum	0.497 ± 0.225	25	0.957 ± 0.188	25	≤0.001
Bansal [37]	µmol/l	Plasma	792.33 ± 124.33	40	989.75 ± 96.80	40	<0.001
Verghese et al. [46]		Serum	0.56 ± 0.04	25	1.58 ± 0.05	25	<0.001

The treatment performed was non-surgical therapy (NST). SD, standard deviation.