Research Article
JAK2 as Predictor of Therapeutic Response in Patients with Chronic Myeloid Leukemia Treated with Imatinib
Table 3
Correlation coefficients for JAK2 levels and the presence of a complete hematological response, as well as early molecular response.
| Variable | Complete hematological response | Early molecular response | r | p-Value | r | p-Value |
| JAK2 levels before imatinib treatment | JAK2 gene | −0.333 | 0.018 | −0.271 | 0.045 | Phosphorylated JAK2 | −0.448 | 0.002 | −0.543 | <0.001 | Total JAK2 | −0.477 | 0.001 | −0.520 | <0.001 | JAK2 levels after 3 months of imatinib treatment | JAK2 gene | −0.605 | <0.001 | −0.654 | <0.001 | Phosphorylated JAK2 | −0.476 | 0.001 | −0.421 | 0.003 | Total JAK2 | −0.141 | 0.192 | −0.157 | 0.166 |
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