Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves

Table 1

Serum marker concentrations and age in patients with lung cancer and benign lung lesions and in healthy subjects.

	Healthy	Lung cancer	P
Year	54.82 ± 12.79	62.93 ± 11.12	<0.001
CEA (ng/mL)	5.87 ± 3.20	37.43 ± 128.73	<0.001
CA125 (U/mL)	13.95 ± 16.56	56.06 ± 138.34	0.003
CY211 (ng/mL)	13.95 ± 16.56	8.57 ± 31.12	0.023
GRP (pg/ml)	48.09 ± 27.11	95.52 ± 158.82	<0.001
NSE (ng/mL)	14.15 ± 7.10	20.75 ± 30.19	<0.001
	Benign lung disease	Lung cancer	P
Year	67.09 ± 14.28	62.93 ± 11.12	<0.001
CEA (ng/mL)	5.85 ± 16.31	37.43 ± 128.73	<0.001
CA125 (U/mL)	44.09 ± 106.99	56.06 ± 138.34	0.46
CY211 (ng/mL)	5.96 ± 26.21	8.57 ± 31.12	0.23
GRP (pg/ml)	57.88 ± 52.42	95.52 ± 158.82	<0.001
NSE (ng/mL)	14.14 ± 10.74	20.75 ± 30.19	<0.001