Research Article
Determination of Tumor Marker Screening for Lung Cancer Using ROC Curves
Table 4
The value of various combinations of lung cancer screening markers in patients with benign lung lesions.
| Benign lung disease | SEN | SPE | PPV | NPV | +LR | −LR | Yden | AUC |
| CEA + NSE▴ | 0.693 | 0.620 | 0.585 | 0.724 | 1.829 | 0.494 | 0.410 | 0.723 | CEA + GRP | 0.730 | 0.584 | 0.575 | 0.737 | 1.758 | 0.461 | 0.426 | 0.667 | GRP + NSE | 0.663 | 0.719 | 0.645 | 0.734 | 2.365 | 0.468 | 0.407 | 0.697 | CEA + GRP + NSE★ | 0.804 | 0.525 | 0.563 | 0.781 | 1.719 | 0.367 | 0.427 | 0.734 |
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