Review Article
Cutaneous Scarring: A Clinical Review
Table 1
Normal, hypertrophic, and keloid scars compared.
| Normal | Hypertrophic | Keloid |
| Confined to edges of original wound | Confined to edges of original wound | Extends beyond edges of wound | Gradual fading and atrophy after maturation | Regresses after initial peak (although often over several years) | Progressive | No treatment required | First-line treatment: silicone patches or gels | First-line treatment: intralesional steroid injection | Best in the elderly | Worst in the young | More common in darker skin | Normal response to TGF-1 | Abnormal response to TGF-1 | Failure of apoptosis |
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