Impaired Healing of a Cutaneous Wound in an Inducible Nitric Oxide Synthase-Knockout Mouse

Figure 1

(a) Macroscopic wound findings of cutaneous excision wound healing in dorsal skin of inducible nitric oxide synthase (iNOS-) knockout (KO) mice and wild type (WT) mice. (b) Unhealed wound area changed in percentage to the original wound area in each time point. At the time points of 3, 6, 8, and 11, the remaining skin defect was larger in KO mice than WT mice with a statistically significant difference. Open bars: WT, filled bars: KO ( animals in each group). Mean ± standard deviation. ; .

(a)

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