Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study

Table 2

Biochemical parameters measured during the course of study.

Parameter	Units	Ref range	Week 0	Week 4	Week 12	Week 24
			Average value ± SEM
Blood glucose	mg/ml	90–120	121.4 ± 5.12	113.66 ± 2.41	113.26 ± 3.16	111.72 ± 3.70
Albumin	g/dl	3.2–4.8	4.36 ± 0.046	4.37 ± 0.054	4.31 ± 0.061	4.35 ± 0.046
Alkaline phosphatase	U/l	42–98	90.33 ± 3.70	85.59 ± 3.37	85.50 ± 3.34	90.60 ± 3.93
ALT	U/l	10–28	16.52 ± 0.96	17.11 ± 1.42	17.2 ± 1.48	21.11 ± 3.2
AST	U/l	<31	22.02 ± 1.07	22.54 ± 1.37	22.43 ± 1.27	27.11 ± 2.44
Bilirubin (direct)	mg/dl	<0.3	0.17 ± 0.015	0.16 ± 0.012	0.17 ± 0.016	0.18 ± 0.013
Bilirubin (indirect)	mg/dl	0–0.9	0.39 ± 0.023	0.37 ± 0.025	0.41 ± 0.033	0.43 ± 0.033
Blood urea nitrogen	mg/dl	7–25	9.06 ± 0.58	10.47 ± 0.52	10.51 ± 0.62	11.71 ± 0.65
Glomerular filtration rate	ml/min/1.73 m^2	≥90	120.17 ± 1.75	122.66 ± 2.12	122.06 ± 2.80	123.13 ± 2.09
Serum calcium	mg/dl	8.8–10.6	9.24 ± 0.077	9.35 ± 0.11	9.23 ± 0.12	9.51 ± 0.064
Serum creatinine	mg/dl	0.5–0.8	0.65 ± 0.014	0.63 ± 0.016	0.64 ± 0.024	0.62 ± 0.015
HOMA index value	—	0.7–2	1.44 ± 0.15	—	—	1.88 ± 0.19