Research Article

Influence of Oral Supplementation of Vitamins A and E on the Effectiveness of Vitiligo Treatment

Table 4

Comparison of biochemical parameters and VASI and DLQI scales before and after treatment.

VariablesGroupBefore treatmentAfter treatment

CAT (U/g Hb × 104)FOTO69.83 (12.45)71.28 (12.51)0.597T
FOTO + WIT64.79 (12.7)68.73 (11.39)0.287T
WIT69.19 (10.65)69.35 (9.29)0.963T

SOD (U/g Hb)FOTO771 (122.1)787.5 (155.5)0.721T
FOTO + WIT740.4 (96.9)749.6 (72.4)0.658T
WIT766.2 (131.7)781.8 (108.6)0.609W

GPX (U/g Hb)FOTO7.35 (4.23)28.7 (61.63)0.233W
FOTO + WIT7.22 (3.82)11.37 (5.47)0.023W
WIT10.09 (5.2)9.78 (4.25)0.836T

wit. A (μg/l)FOTO0.57 (0.17)0.53 (0.28)<0.001W
FOTO + WIT0.66 (0.43)0.85 (0.18)<0.001W
WIT0.57 (0.15)0.68 (0.18)0.059T

wit. E (μg/l)FOTO8.8 (8.12)9.05 (7.93)0.605W
FOTO + WIT2.83 (2.75)16.65 (15.62)0.001W
WIT4.48 (3.39)11.02 (7.8)0.004W

Plasma MDA (nmol/ml)FOTO0.53 (0.33)0.55 (0.29)0.730W
FOTO + WIT0.58 (0.31)0.69 (0.6)0.691W
WIT0.49 (0.29)0.47 (0.27)0.733W

MDA of erythrocytes (nmol/g)FOTO0.58 (0.3)0.8 (0.35)0.048T
FOTO + WIT0.49 (0.31)0.67 (0.35)0.256W
WIT0.53 (0.27)0.75 (0.35)0.065T

VASI (points)FOTO19.13 (10.53)11.97 (7.17)0.001W
FOTO + WIT18.08 (5.46)11.13 (4.12)<0.001T
WIT16.1 (14.37)15.86 (14.1)0.018W

DLQI (points)FOTO8.13 (3.9)6.5 (3.25)0.002W
FOTO + WIT10.4 (4.63)8.5 (4.22)0.013W
WIT8.13 (5.48)7.8 (5.05)0.138W

Mean (SD), standard deviation. WAnalyzed by the Wilcoxon test; Tanalyzed by the dependent t-test.