Research Article

Dupilumab Therapy of Prurigo Nodularis: A Single-Center, Real-Life Observational Study

Table 1

Basic information of patients with prurigo nodularis.

VariablesValue n (%)

Sex
 Male22 (76%)
 Female7 (24%)
Age56.55 ± 3.23
Disease duration4.87 ± 0.94
Comorbidities
 Hypertension4 (13.79%)
 Diabetes2 (6.90%)
 Coronary heart disease1 (3.45%)
 Allergic rhinitis3 (10.34%)
 Eczema11 (37.93%)
 Depression3 (10.34%)
 Anxiety5 (17.24%)
 Sleep disorders15 (51.72%)
 HIV1 (3.45%)
Family history
 Allergic diseases2 (6.90%)
 Eczema1 (3.45%)
Laboratory examination
 Elevated eosinophil count7 (24.14%)
 Elevated Ig E levels22 (20.69%)
Previous treatment
 Antihistamine treatment29 (100%)
 Topical glucocorticoids29 (100%)
 Oral and/or intramuscular injection glucocorticoids19 (65.52%)
 Oral thalidomide6 (20.69%)
 Microneedle therapy4 (13.79%)