Side-by-Side Comparative Study of a Moisturizer and Topical Tacrolimus for Treating Mild to Moderate Atopic Dermatitis: A Randomized Single-Blinded Clinical Trial

Figure 3

Mean values of (a) mEASI, (b) hydration, (c) TEWL, (d) MI, and (e) EI throughout the follow-up visits (mean ± standard error). (a) Differences in mEASI scores between the moisturizer and tacrolimus groups were significantly greater at week 4 than that at baseline. (b) Hydration levels were significantly increased at week 2 and week 4 compared to baseline in both groups. (c, d At week 4, TEWL and MI values were decreased in both the moisturizer and tacrolimus groups although they were not statistically significant. (e) At week 4, EI scores were increased in the tacrolimus group but decreased in the moisturizer group, although these increases or decreases were not statistically significant. mEASI, modified Eczema Area and Severity Index; TEWL, transepidermal water loss; MI, melanin index; EI, erythema index, ns; not significant. ; ; .

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