Dermatologic Therapy

Research Article

The Efficacy and Safety of a Low-Fluence 1064 nm Picosecond ND-YAG Laser Compared with Those of a Low-Fluence Photoacoustic Therapy Pulsed (PTP) Mode 1064 nm Q-Switched ND-YAG Laser for Treatment of Melasma: A Prospective Split-Face Study

Dermoscopic scores of the pigmentary and vascular elements in melasma at week 0 and week 16 in the 1064 nm picosecond ND-YAG laser group.


Dermoscopic findings		Not detected no. (%)	Hardly detected no. (%)	Detected no. (%)	Obvious no. (%)	value

Pseudoreticular network	Week 0	3 (20)	1 (6.7)	5 (33.3)	6 (40)	0.043 ()
Pseudoreticular network	Week 16	3 (20)	3 (20)	9 (60)	0 (0)	0.043 ()

Globular pattern	Week 0	1 (6.7)	1 (6.7)	7 (46.7)	6 (40)	0.032 ()
Globular pattern	Week 16	0 (0)	8 (53.3)	5 (33.3)	2 (13.3)	0.032 ()

Dotted pattern	Week 0	6 (40)	7 (46.7)	1 (6.7)	1 (6.7)	0.985
Dotted pattern	Week 16	7 (46.7)	6 (40)	1 (6.7)	1 (6.7)	0.985

Arcuate pattern	Week 0	10 (66.7)	2 (13.3)	2 (13.3)	1 (6.7)	0.790
Arcuate pattern	Week 16	11 (73.3)	2 (13.3)	2 (13.3)	0 (0)	0.790

Visible telangiectasia	Week 0	5 (33.3)	4 (26.7)	3 (20)	3 (20)	0.902
Visible telangiectasia	Week 16	6 (40)	3 (20)	4 (26.7)	2 (13.3)	0.902

Perifollicular pigmentation	Week 0	1 (6.7)	4 (26.7)	6 (40)	4 (26.7)	0.260
Perifollicular pigmentation	Week 16	3 (20)	7 (46.7)	4 (26.7)	1 (6.7)	0.260

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