Is Tranexamic Acid Use Effective in Preventing Postinflammatory Hyperpigmentation after Laser Treatment? A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

Study (year)	Country	Treated diseases	Treated area	Mean age or age range (Y)	SPT	F/N	Follow-up time (m)
Tawfic et al. (2019) [11]	Egypt	Melasma	Face	39.61 ± 6.71	III–V	28/28	6
Wanitphakdeedecha et al. (2020) [12]	Thailand	Melasma	Face	48.00 ± 10.00	III–V	44/46	6
Sirithanabadeekul and Srieakpanit (2018) [13]	Thailand	Solar lentigines	Forearm	60.88 ± 6.64	III–V	18/25	3
Laothaworn and Juntongjin (2018) [14]	Thailand	Melasma	Face	44.79 ± 7.79	III–V	24/25	2
Rutnin et al. (2019) [15]	Thailand	Solar lentigines	Forearm	18–70	II–V	38/40	3
Shin et al. (2013) [16]	Korea	Melasma	Face	18–55	III-IV	48/48	2
Laothaworn et al. (2016) [17]	Thailand	Melasma	Face	33–53	III–V	10/10	2

Y, years; m, months; F, female; N, total number of patients; SPT, Fitzpatrick skin type.