Research Article

Ultraviolet A Combined with Narrow-Band Ultraviolet B is an Effective Treatment Modality for Early Folliculotropic Mycosis Fungoides and Early Mycosis Fungoides Refractory to Narrow-Band Ultraviolet B: A Retrospective Cohort Study

Table 1

Characteristics of patients with early-stage mycosis fungoides treated with UVA combined with NBUVB.

Type of MFGender/age#, median (range)Stage of diseaseTreatments prior to UVA + NBUVB and response

FMF: 39 patientsM-24, F-15/
44 y (4–82)
IA-17
IB-22
Topical application: TCS: all; mechlorethamine gel: 2 SD
Phototherapy: NBUVB: 8 (6 PR, 2 SD); systemic PUVA: 1 CR
Other treatments: acitretin, IFN α: 1 SD; MTX: 2 SD; LEB: 1 CR

Non-FMF: 12 patientsM-9, F-3/
50 y (7–83)
IA-2
IB-9
IIA-1
Topical application: TCS: all; mechlorethamine gel: 3 (2 SD, 1 stopped&)
Phototherapy: NBUVB: 9 (6 PR, 3 SD); systemic PUVA: 1 CR
Other treatments: MTX: 1 SD

CR, complete response; F, female; FMF, folliculotropic mycosis fungoides; IFN α, interferon α; LEB, localized electron beam; M, male; MTX, methotrexate; MF, mycosis fungoides; NBUVB, narrow-band ultraviolet B; PR, partial response; PUVA, psoralen plus ultraviolet A; SD, stable disease; TCS, topical corticosteroids; UVA, ultraviolet A; y, years. #Age at initiation of UVA and NBUVB. One patient had relatively thick plaques. &Stopped treatment due to contact dermatitis.