Macrophage Migration Inhibitory Factor and Gene Polymorphism (rs755622G>C) in Unstable Vitiligo Patients

Table 1

Tissue levels of MIF among the study groups and tissue levels of MIF among the included patients in terms of response to therapy.

Variables	Cases (n = 50)	Controls (n = 50)	p-value
Pretherapy tissue MIF (median and IQR, μg/gm tissue proteins)	0.36 (0.17–0.75)	0.18 (0.08–0.38)	0.002
Posttherapy tissue MIF (median and IQR, μg/g tissue proteins)	0.13 (0.04–0.56)	0.18 (0.08–0.38)	0.235
value	<0.001	—	—
Variables	Cases (n = 50)
	Minimal to mild improvement (n = 25)	Moderate to marked improvement (n = 25)	-value
Pretherapy tissue MIF (median and IQR, μg/g tissue proteins)	0.29 (0.12–0.50)	0.24 (0.13–0.60)	0.617
Posttherapy tissue MIF (median and IQR, μg/g tissue proteins)	0.16 (0.06–0.37)	0.18 (0.058–0.59)	0.424
value	<0.001	<0.001	—

The Mann–Whitney U test was used for continuous data. ^∗P value <0.05 is considered significant.