Macrophage Migration Inhibitory Factor and Gene Polymorphism (rs755622G>C) in Unstable Vitiligo Patients

Table 3

Genotypes and allele frequencies of MIF rs755622G>C single nucleotide polymorphism among the included cases in terms of response to therapy.

Study groups	Variables
	MIF rs755622G>C genotypes														MIF rs755622G>C alleles
	GG		GC		CC		GG + GC		CC		GG		GC + CC		G		C
	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
Minimal to mild improvement (n = 25)	11	44	10	40	4	16	21	84	4	16	11	44	14	56	32	64	18	36
Moderate to marked improvement (n = 25)	17	68	7	28	1	4	24	96	1	4	17	68	8	32	41	82	9	18
-value (χ^2)	0.027 (7.230)						0.046 (4.000)				0.016 (5.844)				0.004 (8.219)
OR (95% CI)	—						0.219 (0.044–1.088)				0.37 (0.164–0.836)				0.390 (0.203–0.750)

The Chi-squared test was used for categorical variables. ^∗P value <0.05 is considered significant. ^∗∗P value <0.01 is considered significant.