The Right Formula for Acne: Importance of Vehicle Formulation in Tazarotene 0.045% Lotion Design, Application, Tolerability, and Efficacy

Figure 2

Polymeric emulsion technology for tazarotene 0.045% lotion. (a) Cryoscanning electron micrograph (10,000x magnification) showing an oil-in-water droplet (diameter ∼1-2 micron) within the 3-d polymeric mesh. (b) This highly spreadable lotion formulation was developed to provide rapid and uniform distribution of tazarotene and moisturizing/hydrating agents while reducing the potential for skin irritation. Reprinted with permission from Eric Guenin: Springer, Am J Clin Dermatol; 50 Years of Topical Retinoids for Acne: Evolution of Treatment; Baldwin et al. [1] Copyright 2021.

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