Review Article
MicroRNAs as Potential Biomarkers for the Diagnosis, Treatment, and Prognosis of Sexually Transmitted Diseases: Recent Advances and Future Directions
Table 1
MiRNAs modulate condyloma acuminatum infection by regulating host proteins.
| miRNA | Target(s) | Action | Experimental strategy | References |
| miR-34a-5p | PD-L1 | Course of disease, wart size, HPV infection subtype, and diagnostic value | In vitro | [11] | miR-143/miR-145 | NRAS, PI3 K p110a, and p-AKT | Dysplasia of cell proliferation | In vitro | [12] | miR-99b | IGF-1R | Dysplasia of cell proliferation | In vitro | [13] | miR-26a | PTEN | Dysplasia of cell proliferation | In vitro | [14] | miR-30a-5p/miR-514a-3p | Atg5, Atg12, Atg3 | Involved in the regulation of the CA autophagy system | In vitro | [15] | miR-22-3p | VEGF | HPV infection type | In vitro | [17] | miR-9 | HK2 | Course of disease, wart size, and HPV infection subtype | In vitro | [23] | miR-149-3p | HE4 | Course of disease, wart size, and HPV infection subtype | In vitro | [22] | miR-143/miR-155 | NRAS, PI3 K p110a, and p-AKT | Course of disease, wart size, and HPV infection subtype | In vitro | [19] | miR-203 | p63 | HPV infection subtype | In vitro | [21] | miR-203 | Survivin | HPV infection subtype | In vitro | [20] |
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