MicroRNAs as Potential Biomarkers for the Diagnosis, Treatment, and Prognosis of Sexually Transmitted Diseases: Recent Advances and Future Directions

Table 2

MiRNAs modulate syphilis infection by regulating host proteins.

miRNA	Target(s)	Action	Experimental strategy	References
miR-195-5p/miR223-3p/miR-589-3p	Several genes	Diagnostic tool and predictor of serological response	In vitro	[27]
miR-101-3p	TLR2 3, UTR	Macrophage cytokine decreased	In vitro	[29]
miR-338-5p	RANBP 17, XPO 1 and XPO 6	Identification of patients with serological fixation and diagnosis of latent syphilis	In vitro	[26]
miR-142-3p	DC	Promoting the progression of syphilis infection	In vitro	[30]