Regulating the Wnt/β-catenin Signaling Pathway Promotes Repigmentation in Vitiligo Using Fire Needle Therapy

Figure 3

Fire needling induces vitiligo repigmentation. (a) Representative images showing the changes before and after treatment. The mice were divided into four groups: the blank group, the inhibitor (Iwr-1) group, the fire needle group, and the sham treatment group. (b) Comparison of the final percentage change in pigmentation among the blank group, Iwr-1 group, fire needle group, and sham group. (c) Haematoxylin and eosin staining was performed on the tail skins of mice in each group (bar = 100 μm). (d) Fontana-Masson staining showing the amount and distribution of melanin in each group (bar = 100 μm).