Original Article

Podophyllum hexandrum-Mediated Survival Protection and Restoration of Other Cellular Injuries in Lethally Irradiated Mice

Figure 8

Effect of P. hexandrum sub-fraction (G-001M) on DNA damage in peripheral blood leucocytes of whole body irradiated (10 Gy) mice. Measurement of DNA damage was done at different time intervals using comet assay in terms of tail length (mean ± SD). Experiments were done in triplicate with three animals in each group. Data points are mean values of 100 cells from each groups. j: Normal versus 15 min 10 Gy; k: l5 min l0 Gy versus 15 min (G-001M + 10 Gy); l: 120 min 10 Gy versus l20 min (G-001M + 10 Gy); m: 24 h 10 Gy versus 24 h (G-001M + 10 Gy) ( , ns, non significant).
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