Aleurites moluccana (L.) Willd. Leaves: Mechanical Antinociceptive Properties of a Standardized Dried Extract and Its Chemical Markers

Figure 6

((a) and (b)) Effects of the A. moluccana extract batch 1, 2, or 3, administered orally (250 mg/kg, 1 h before), in the mechanical hypernociception induced by i.d. injection of carrageenan (300 μg/paw) in mice. Each group represents the mean of 5 to 8 animals, and the vertical lines indicate the SEM. Significantly different from the control values **𝑃<0.01 and significantly different from the saline group ^#𝑃<0.001 (two-way ANOVA followed by Bonfferroni’s post-hoc test and one-way ANOVA followed by Dunnett’s post-hoc test).

(a)

(b)