Efficacy of Goshajinkigan for Peripheral Neurotoxicity of Oxaliplatin in Patients with Advanced or Recurrent Colorectal Cancer

Table 6

Tumor response to treatment (RECIST).

	Group A	Group B	Group C	Group D
CR	0	0	0	0
PR	6	5	9	20
SD	4	5	10	19
PD	1	3	1	3
NE	0	1	1	2
Response Rate	6 (54.5%)	5 (35.7%)	9 (42.9%)	20 (45.5%)
(CR+PR)	(𝑃=.589)	(𝑃=.522)	(𝑃=.844)
Disease Control Rate	10 (90.9%)	10 (71.4%)	19 (90.5%)	39 (88.6%)
(CR+PR+PD)	(𝑃=.829)	(𝑃=.121)	(𝑃=.823)

Group A: GJG, Group B: Ca/Mg, Group C: GJG+Ca/Mg, Group D: no therapy.
CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease; NE: no evaluate.
P-values are for Groups A, B, and C versus. Group D by the 𝜒²-test.
GJG: goshajinkigan, Ca: calcium gluconate, Mg: magnesium sulfate.