Cranberry and Grape Seed Extracts Inhibit the Proliferative Phenotype of Oral Squamous Cell Carcinomas
Figure 9
Proliferation inhibition of CAL27 comparison: PAC, CE and GSE. Previous results of proliferation inhibition of CAL27 with PAC were compared with the results of the current investigation. GIMAX concentration of purified GSE-derived PAC (50 μg/ml) exhibited a slightly more robust inhibition of CAL27 growth than CE or GSE (a). Comparison of current results with previous observations using purified GSE-derived PAC demonstrated that although all treatments (PAC, CE, GSE) reduced cell number and inhibited proliferation, to varying degrees, purified GSE-derived PAC most decreased cell viability (–72%) and cell spreading (–80%) (b). A colour version of this figure is available online as supplementary data.
