An Angiotensin I Converting Enzyme Polymorphism Is Associated with Clinical Phenotype When Using Differentiation-Syndrome to Categorize Korean Bronchial Asthma Patients

Table 4

Comparison of the frequency of ACE I/D polymorphism between male and female DSGA and ESGA patients.

		Allele frequency (%)		Odds ratio	P-value
	N	D	I	(95% CI)
Male	33	39 (59.00)	27 (40.91)	0.9962	.9907^a
Female	48	59 (59.00)	41 (41.00)	(0.5295–1.8745)
Male
DSGA	19	23 (60.53)	15 (39.47)	1.15	.8051^b
ESGA	14	16 (57.14)	12 (42.86)	(0.4266–3.1000)
Female
DSGA	33	44 (66.67)	22 (33.33)	3.4545	.0043^b
ESGA	15	11 (36.67)	19 (63.33)	(1.4019–8.5125)
		Genotype frequency (%)			P-value	HWE
	N	D/D	I/D	I/I		P-value
Male	33	12 (36.36)	15 (45.45)	6 (18.18)	.9605^c	.7311
Female	48	16 (33.33)	23 (47.92)	9 (18.75)		.8852
Male
DSGA	19	8 (42.11)	7 (36.84)	6 (18.18)	.5795^d	.3182
ESGA	14	4 (28.57)	8 (57.14)	2 (14.29)		.5329
Female
DSGA	33	15 (45.45)	14 (42.42)	4 (12.12)	.0126^d	.794
ESAG	15	1 (6.67)	9 (60.00)	5 (33.33)		.2583

DSGA, Deficiency Syndrome Group of Asthma; ESG, Excess Syndrome Group of Asthma; HWE, Hardy-Weinberg equation.
^aMale versus female using the chi-squared test with a 2×2 contingency table.
^bDSGA versus ESGA sex distinction using the Fisher's test with 2×2 contingency table.
^cMale versus female using the chi-squared test with 3×2 contingency table.
^dDSGA versus ESGA sex distinction using the Fisher test with 3×2 contingency table.