Oral Treatment with Extract of Agaricus blazei Murill Enhanced Th1 Response through Intestinal Epithelial Cells and Suppressed OVA-Sensitized Allergy in Mice
Figure 4
Effect of ABME on the production of the Th2 cytokines IL-4 and 5 from antigen-restimulated splenocytes in OVA-sensitized mice. Two days after the last OVA injection, the spleen cells isolated from each mouse were restimulated with 25 g/ml OVA. After incubation at 37oC for 72 h, the levels of IL-4 (a) and IL-5 (b) in the culture supernatants were determined using a cytometric bead array immunoassay. Values represent the means ± S.E. of 5 mice in each group. ,, significantly different from the values of the control group.
