N-Acetylcysteine an Allium Plant Compound Improves High-Sucrose Diet-Induced Obesity and Related Effects

Table 2

General characteristics, nutritional parameters and glycemic response of the rats.

Determinations	Groups
	C	HS-HS	HS-N	HS-CN
Initial body weight (g)	295.1 ± 7.5	301.5 ± 6.5	307.6 ± 6.3	304.6 ± 2.5
Final body weight (g)	388.7 ± 2.7b	446.4 ± 3.6a,c,d	403.7 ± 6.2b	407.5 ± 8.6b
Body weigh gain (g)	93.6 ± 3.5b	119.3 ± 3.2a,c,d	77.1 ± 14.3b	81.9 ± 11.6b
Food consumption (g/day)	28.04 ± 6.07b,c,d	21.29 ± 1.87a	18.76 ± 2.91a	21.11 ± 2.12a
Body mass index (g/cm^2)	0.60 ± 0.02b	0.71 ± 0.01a,c,d	0.64 ± 0.03b	0.65 ± 0.03b
Surface area (g^0.7)	64.9 ± 2.3b	71.6 ± 1.6a,c,d	66.7 ± 1.2b	67.2 ± 1.4b
Lee-index (g/cm)	0.29 ± 0.01	0.31 ± 0.01	0.29 ± 0.02	0.29 ± 0.01
Drinking solution ingestion (ml/day)	48.3 ± 7.9b,c,d	35.6 ± 8.6a	30.4 ± 2.4a	32.5 ± 2.1a
Energy intake (kcal/day)	80.2 ± 17.4b,c,d	68.8 ± 6.1a	60.6 ± 7.3a	60.4 ± 5.9a
Feed efficiency (%)	5.30 ± 0.52b,d	7.88 ± 0.61a,c,d	5.78 ± 0.48b	6.17 ± 0.43a,b
NAC intake (mg/day)	0.00c,d	0.00c,d	0.061 ± 0.001a,b	0.065 ± 0.002a,b
Glycemic response (mg/dl h)	70.5 ± 1.5b	87.1 ± 3.1a,c,d	63.5 ± 6.5b	60.4 ± 6.3b

C, control rats; HS-HS, rats receiving high-sucrose diet and water; HS-N, rats receiving high-sucrose diet and water for 22 days, giving NAC in its drinking water for more than 22 days; HS-CN, rats receiving high-sucrose diet and water for 22 days, giving NAC and control chow for more than 22 days.
Values are given as mean ± SD of the mean.
aValues significantly different from C group, P < .01; bValues significantly different from HS-HS group, P< .01; cValues significantly different from HS-N group, P< .01; dValues significantly different from HS-CN group, P< .01.