Apoptotic Cell Death and Inhibition of Wnt/β-Catenin Signaling Pathway in Human Colon Cancer Cells by an Active Fraction (HS7) from Taiwanofungus camphoratus
Figure 8
Inhibitory effects of HS7 on the expressions of Tcf/β-catenin downstream genes in HT29 cells. (a) Cells were treated with HS7 (2.5–10 μg/mL) for 48 h. Survivin mRNA expression was evaluated by RT-PCR. Densitometric analysis of RT-PCR results normalized to GAPDH was shown as bar graph. Results represent the mean of 3 experiments ± SD. (b) Cells were exposed to 10 μg/mL HS7 for 48 h, and the expressions of c-Myc, CyclinD1, MMP7, and MT1-MMP mRNAs were evaluated by RT-PCR. *; ** compared with control.
