Flourensia cernua: Hexane Extracts a Very Active Mycobactericidal Fraction from an Inactive Leaf Decoction against Pansensitive and Panresistant Mycobacterium tuberculosis

Table 5

Absolute mycobactericidal activity against RMtb in F. cernua leaf preparations^a.

Extract (solvent)	Fraction (solvent)	Extraction or fractionation method	AMA^b (MBU)	ΣAMA^c	NAMA^d
A (W)		DC	ND	NQ	NQ
	A1 (n-Hex)	LLP	196,176
	A2 (EtOAc)	LLP	9,150
	A3 (n-BuOH)	LLP	6,478	211,804	1.0
B (EtOH)		StMC	76,500		0.36
	B1 (n-Hex)	LLP	37,791
	B2 (EtOAc)	LLP	65,331
	B3 (n-BuOH)	LLP	2,104	105,226	0.50
C (EtOH)		SXH	93,900		0.44
	C1 (n-Hex)	LLP	64,228
	C2 (EtOAc)	LLP	35,588
	C3 (n-BuOH)	LLP	4,977	104,793	0.49
D (EtOH)		UsMC	68,100		0.32
	D1 (n-Hex)	LLP	34,459
	D2 (EtOAc)	LLP	35,140
	D3 (n-BuOH)	LLP	7,695	77,294	0.36
E (EtOH)		SkMC	92,700		0.44
	E1 (n-Hex)	LLP	84,172
	E2 (EtOAc)	LLP	16,037
	E3 (n-BuOH)	LLP	3,106	103,315	0.49
F (n-Hex)		StMc	108,000
G (EtOAc)		StMc	57,600
H (EtOH)		StMc	49,800	215,400	1.02
I (n-Hex)		SXH	57,000
J (EtOAc)		SXH	24,600
K (EtOH)		SXH	36,300	117,900	0.56
L (n-Hex)		UsMC	69,000
M (EtOAc)		UsMC	11,700
N (EtOH)		UsMC	8,250	88,950	0.42
O (n-Hex)		SkMC	75,000
P (EtOAc)		SkMC	16,500
Q (EtOH)		SkMC	51,300	142,800	0.67

^aObtaining of extracts and their fractions as well as their correspondent yields and MBC is described in the footnotes of Tables 1–3. Definitions, acronyms, symbols, and calculations are depicted Section 2 or in the foot note of Table 4.