Biological Evaluation of Polyherbal Ayurvedic Cardiotonic Preparation “Mahamrutyunjaya rasa”

Figure 4

Effect of formulations F1, F2, and F3 (a) 25 mg/kg and (b) 50 mg/kg on Heart weight/body weight ratio (HW/BW). Group I (1% solution of tween 80 in water followed by normal saline (2 mL/kg, s.c. twice at an interval of 24 h)); Group II (1% tween 80 followed by ISO (25 mg/kg, s.c. twice at an interval of 24 h)); Group III, VI, IX: (50 mg/kg dose of F1, F2, and F3, resp., followed by normal saline (2 mL/kg, s.c. twice at an interval of 24 h)); Group IV, VII, X: (administered orally with 25 mg/kg dose of F1, F2, and F3, resp., followed by ISO (25 mg/kg, s.c. twice at an interval of 24 h)); Group V, VIII, XI (administered orally with 50 mg/kg dose of F1, F2, and F3, resp., followed by ISO (25 mg/kg, s.c. twice at an interval of 24 h)). *Compared with control group.