Epigenetics in Traditional Chinese Pharmacy: A Bioinformatic Study at Pharmacopoeia Scale

Figure 8

Pattern of utilization of epigenetic mechanisms over TCM positions. Medicinals in a formula can be differentiated by their positions in the formula into Monarch, Minister, Assistant and Guide. The mechanism-specific interactivity of the Monarch (and other) medicinals in the 198 epigenetic TCMFs is calculated and summed. The lighter the shades, the larger the interactivity.